Autonomous systems are on their way from an exotic system species to a mainstream technology, were they even reach safety critical and high assurance applications. Yet, efficient design concepts providing the required behavioral guarantees while keeping the benefits of autonomous intelligence are still an open topic, in theory and even more so in engineering practice. Some approaches rely on centralized guidance via infrastructure, others extend individual component capabilities by protective, often model based, functions. Another differentiation is the use of human support in unclear situations, such as in level 4 vehicle automation, vs. independent management with function degradation (e.g. safety layers). The workshop plans to provide examples from very different areas, such as road traffic, UAVs, human assistive robotics, and facility management. The design concepts have a high societal and economic relevance, including legal aspects, such as certification and liability.